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A Scalable System for Production of Functional Pancreatic Progenitors from Human Embryonic Stem Cells
Development of a human embryonic stem cell (hESC)-based therapy for type 1 diabetes will require the translation of proof-of-principle concepts into a scalable, controlled, and regulated cell manufacturing process. We have previously demonstrated that hESC can be directed to differentiate into pancr...
Autores principales: | Schulz, Thomas C., Young, Holly Y., Agulnick, Alan D., Babin, M. Josephine, Baetge, Emmanuel E., Bang, Anne G., Bhoumik, Anindita, Cepa, Igor, Cesario, Rosemary M., Haakmeester, Carl, Kadoya, Kuniko, Kelly, Jonathan R., Kerr, Justin, Martinson, Laura A., McLean, Amanda B., Moorman, Mark A., Payne, Janice K., Richardson, Mike, Ross, Kelly G., Sherrer, Eric S., Song, Xuehong, Wilson, Alistair Z., Brandon, Eugene P., Green, Chad E., Kroon, Evert J., Kelly, Olivia G., D’Amour, Kevin A., Robins, Allan J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356395/ https://www.ncbi.nlm.nih.gov/pubmed/22623968 http://dx.doi.org/10.1371/journal.pone.0037004 |
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