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MyoD-dependent regulation of NF-κB activity couples cell-cycle withdrawal to myogenic differentiation

BACKGROUND: Mice lacking MyoD exhibit delayed skeletal muscle regeneration and markedly enhanced numbers of satellite cells. Myoblasts isolated from MyoD(-/-) myoblasts proliferate more rapidly than wild type myoblasts, display a dramatic delay in differentiation, and continue to incorporate BrdU af...

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Detalles Bibliográficos
Autores principales: Parker, Maura H, von Maltzahn, Julia, Bakkar, Nadine, Al-Joubori, Ban, Ishibashi, Jeff, Guttridge, Denis, Rudnicki, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356597/
https://www.ncbi.nlm.nih.gov/pubmed/22541644
http://dx.doi.org/10.1186/2044-5040-2-6