Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature

BACKGROUND: Extragonadal localization of germ cell tumors (GCTs) is rare; to the best of our knowledge, a location in the soft tissue of the arm has never been previously reported in the literature. CASE PRESENTATION: We report the case of a 37-year-old man who presented with a primary malignant mix...

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Autores principales: Benali, Hicham Ait, Lalya, lssam, Allaoui, Mohamed, Benmansour, Aniss, Elkhanoussi, Basma, Benjelloun, Samir, Benjaafar, Noureddine, Elyaacoubi, Mourad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356599/
https://www.ncbi.nlm.nih.gov/pubmed/22540884
http://dx.doi.org/10.1186/1477-7819-10-69
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author Benali, Hicham Ait
Lalya, lssam
Allaoui, Mohamed
Benmansour, Aniss
Elkhanoussi, Basma
Benjelloun, Samir
Benjaafar, Noureddine
Elyaacoubi, Mourad
author_facet Benali, Hicham Ait
Lalya, lssam
Allaoui, Mohamed
Benmansour, Aniss
Elkhanoussi, Basma
Benjelloun, Samir
Benjaafar, Noureddine
Elyaacoubi, Mourad
author_sort Benali, Hicham Ait
collection PubMed
description BACKGROUND: Extragonadal localization of germ cell tumors (GCTs) is rare; to the best of our knowledge, a location in the soft tissue of the arm has never been previously reported in the literature. CASE PRESENTATION: We report the case of a 37-year-old man who presented with a primary malignant mixed non-seminomatous GCT (teratocarcinoma variety) in the right arm, treated by a combination of cisplatin-based chemotherapy and surgery. After 18 months of close follow-up, no locoregional recurrence or distant metastases have been detected. CONCLUSIONS: A combination of chemotherapy and surgery is the most appropriate treatment strategy for extragonadal GCTs, to ensure both local and systemic control.
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spelling pubmed-33565992012-05-20 Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature Benali, Hicham Ait Lalya, lssam Allaoui, Mohamed Benmansour, Aniss Elkhanoussi, Basma Benjelloun, Samir Benjaafar, Noureddine Elyaacoubi, Mourad World J Surg Oncol Case Report BACKGROUND: Extragonadal localization of germ cell tumors (GCTs) is rare; to the best of our knowledge, a location in the soft tissue of the arm has never been previously reported in the literature. CASE PRESENTATION: We report the case of a 37-year-old man who presented with a primary malignant mixed non-seminomatous GCT (teratocarcinoma variety) in the right arm, treated by a combination of cisplatin-based chemotherapy and surgery. After 18 months of close follow-up, no locoregional recurrence or distant metastases have been detected. CONCLUSIONS: A combination of chemotherapy and surgery is the most appropriate treatment strategy for extragonadal GCTs, to ensure both local and systemic control. BioMed Central 2012-05-19 /pmc/articles/PMC3356599/ /pubmed/22540884 http://dx.doi.org/10.1186/1477-7819-10-69 Text en Copyright ©2012 Ait Benali et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Benali, Hicham Ait
Lalya, lssam
Allaoui, Mohamed
Benmansour, Aniss
Elkhanoussi, Basma
Benjelloun, Samir
Benjaafar, Noureddine
Elyaacoubi, Mourad
Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
title Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
title_full Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
title_fullStr Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
title_full_unstemmed Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
title_short Extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
title_sort extragonadal mixed germ cell tumor of the right arm: description of the first case in the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356599/
https://www.ncbi.nlm.nih.gov/pubmed/22540884
http://dx.doi.org/10.1186/1477-7819-10-69
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