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Update on a Pharmacokinetic-Centric Alternative Tier II Program for MMT—Part II: Physiologically Based Pharmacokinetic Modeling and Manganese Risk Assessment

Recently, a variety of physiologically based pharmacokinetic (PBPK) models have been developed for the essential element manganese. This paper reviews the development of PBPK models (e.g., adult, pregnant, lactating, and neonatal rats, nonhuman primates, and adult, pregnant, lactating, and neonatal...

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Detalles Bibliográficos
Autores principales:	Taylor, Michael D., Clewell, Harvey J., Andersen, Melvin E., Schroeter, Jeffry D., Yoon, Miyoung, Keene, Athena M., Dorman, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356703/ https://www.ncbi.nlm.nih.gov/pubmed/22645610 http://dx.doi.org/10.1155/2012/791431

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