Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats

This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY). Authors demonstrated the reduction of ATP-sensitive potassium channels is resposible for this change using immunoblotting analy...

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Detalles Bibliográficos
Autores principales: Lee, Liang-Ming, Lu, Chih-Cheng, Chung, Hsien-Hui, Cheng, Juei-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356749/
https://www.ncbi.nlm.nih.gov/pubmed/22645476
http://dx.doi.org/10.1100/2012/941685
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author Lee, Liang-Ming
Lu, Chih-Cheng
Chung, Hsien-Hui
Cheng, Juei-Tang
author_facet Lee, Liang-Ming
Lu, Chih-Cheng
Chung, Hsien-Hui
Cheng, Juei-Tang
author_sort Lee, Liang-Ming
collection PubMed
description This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY). Authors demonstrated the reduction of ATP-sensitive potassium channels is resposible for this change using immunoblotting analysis and the decrease of action induced by diazoxide. This view is not mentioned before and is the first one reporting this result.
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spelling pubmed-33567492012-05-29 Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats Lee, Liang-Ming Lu, Chih-Cheng Chung, Hsien-Hui Cheng, Juei-Tang ScientificWorldJournal Research Article This paper shows a new finding about the decrease of relaxative response to loperamide in prostate of spontaneously hypertensive rats (SHR) as compare to normal rats (WKY). Authors demonstrated the reduction of ATP-sensitive potassium channels is resposible for this change using immunoblotting analysis and the decrease of action induced by diazoxide. This view is not mentioned before and is the first one reporting this result. The Scientific World Journal 2012-05-03 /pmc/articles/PMC3356749/ /pubmed/22645476 http://dx.doi.org/10.1100/2012/941685 Text en Copyright © 2012 Liang-Ming Lee et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Lee, Liang-Ming
Lu, Chih-Cheng
Chung, Hsien-Hui
Cheng, Juei-Tang
Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
title Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
title_full Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
title_fullStr Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
title_full_unstemmed Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
title_short Prostatic Relaxation Induced by Loperamide Is Reduced in Spontaneously Hypertensive Rats
title_sort prostatic relaxation induced by loperamide is reduced in spontaneously hypertensive rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356749/
https://www.ncbi.nlm.nih.gov/pubmed/22645476
http://dx.doi.org/10.1100/2012/941685
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