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PaGeFinder: quantitative identification of spatiotemporal pattern genes

Summary: Pattern Gene Finder (PaGeFinder) is a web-based server for on-line detection of gene expression patterns from serial transcriptomic data generated by high-throughput technologies like microarray or next-generation sequencing. Three particular parameters, the specificity measure, the dispers...

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Detalles Bibliográficos
Autores principales: Pan, Jian-Bo, Hu, Shi-Chang, Wang, Hao, Zou, Quan, Ji, Zhi-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356841/
https://www.ncbi.nlm.nih.gov/pubmed/22492640
http://dx.doi.org/10.1093/bioinformatics/bts169
Descripción
Sumario:Summary: Pattern Gene Finder (PaGeFinder) is a web-based server for on-line detection of gene expression patterns from serial transcriptomic data generated by high-throughput technologies like microarray or next-generation sequencing. Three particular parameters, the specificity measure, the dispersion measure and the contribution measure, were introduced and implemented in PaGeFinder to help quantitative and interactive identification of pattern genes like housekeeping genes, specific (selective) genes and repressed genes. Besides the on-line computation service, the PaGeFinder also provides downloadable Java programs for local detection of gene expression patterns. Availability: http://bioinf.xmu.edu.cn:8080/PaGeFinder/index.jsp Contact: appo@xmu.edu.cn; zouquan@xmu.edu.cn