Cargando…

Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis

Objective To assess the effect of tranexamic acid on blood transfusion, thromboembolic events, and mortality in surgical patients. Design Systematic review and meta-analysis. Data sources Cochrane central register of controlled trials, Medline, and Embase, from inception to September 2011, the World...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ker, Katharine, Edwards, Phil, Perel, Pablo, Shakur, Haleema, Roberts, Ian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group Ltd. 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356857/ https://www.ncbi.nlm.nih.gov/pubmed/22611164 http://dx.doi.org/10.1136/bmj.e3054

Ejemplares similares

Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial
por: Ker, Katharine, et al.
Publicado: (2012)

Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms
por: Roberts, Ian, et al.
Publicado: (2017)

Giving tranexamic acid to reduce surgical bleeding in sub-Saharan Africa: an economic evaluation
por: Guerriero, Carla, et al.
Publicado: (2010)

HALT-IT - tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial
por: Roberts, Ian, et al.
Publicado: (2014)

Tranexamic acid for gastrointestinal bleeding: can a reduction in the risk of death be discounted? A systematic review and meta-analysis of individual patient data from 64 724 bleeding patients
por: Ker, Katharine, et al.
Publicado: (2023)

Cost-Effectiveness Analysis of Administering Tranexamic Acid to Bleeding Trauma Patients Using Evidence from the CRASH-2 Trial
por: Guerriero, Carla, et al.
Publicado: (2011)

Tranexamic acid for post-partum haemorrhage: What, who and when
por: Brenner, Amy, et al.
Publicado: (2019)

Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients
por: Ageron, Francois-Xavier, et al.
Publicado: (2020)

Tranexamic acid for the prevention of postpartum bleeding: Protocol for a systematic review and individual patient data meta-analysis
por: Ker, Katharine, et al.
Publicado: (2023)

Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial
por: Roberts, Ian, et al.
Publicado: (2012)

Exploring redundant research into the effect of tranexamic acid on surgical bleeding: further analysis of a systematic review of randomised controlled trials
por: Ker, Katharine, et al.
Publicado: (2015)

A cost-effectiveness and value of information analysis to inform future research of tranexamic acid for older adults experiencing mild traumatic brain injury
por: Williams, Jack, et al.
Publicado: (2022)

Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury
por: Perel, Pablo, et al.
Publicado: (2008)

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial
por: Ker, Katharine, et al.
Publicado: (2018)

CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial
por: Dewan, Yashbir, et al.
Publicado: (2012)

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan
por: Mahmood, Abda, et al.
Publicado: (2019)

Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation
por: Dallaku, Kastriot, et al.
Publicado: (2017)

Effects of tranexamic acid treatment in severely and non‐severely injured trauma patients
por: Ageron, Francois‐Xavier, et al.
Publicado: (2022)

What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies
por: Picetti, Roberto, et al.
Publicado: (2019)

Economic evaluation of tranexamic acid for the treatment of acute gastrointestinal bleeding: a cost-effectiveness analysis using data from the HALT-IT randomised controlled trial
por: Bazeer, Nuha, et al.
Publicado: (2022)

The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial
por: Shakur, Haleema, et al.
Publicado: (2016)

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients
por: Gayet-Ageron, Angèle, et al.
Publicado: (2018)

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS])
por: Mahmood, Abda, et al.
Publicado: (2017)

Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study
por: Dallaku, Kastriot, et al.
Publicado: (2016)

Tranexamic acid for treatment of women with post-partum haemorrhage in Nigeria and Pakistan: a cost-effectiveness analysis of data from the WOMAN trial
por: Li, Bernadette, et al.
Publicado: (2018)

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: Statistical analysis plan for the WOMAN-2 trial: an international, randomised, placebo-controlled trial
por: Collier, Tim, et al.
Publicado: (2023)

Alternative routes to intravenous tranexamic acid for postpartum hemorrhage: A systematic search and narrative review
por: Shakur‐Still, Haleema, et al.
Publicado: (2022)

The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial
por: Brenner, Amy, et al.
Publicado: (2018)

Tranexamic acid: less bleeding and less thrombosis?
por: Godier, Anne, et al.
Publicado: (2012)

Predicting early death in patients with traumatic bleeding: development and validation of prognostic model
por: Perel, Pablo, et al.
Publicado: (2012)

Effect of tranexamic acid on thrombotic events and seizures in bleeding patients: a systematic review and meta-analysis
por: Murao, Shuhei, et al.
Publicado: (2021)

The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial
por: Shakur, Haleema, et al.
Publicado: (2010)

Tranexamic Acid: A Recipe for Saving Lives in Traumatic Bleeding
por: Roberts, Ian
Publicado: (2012)

Tranexamic Acid – a Recipe for Saving Lives in Traumatic Bleeding
por: Roberts, Ian
Publicado: (2011)

Physiologically based modelling of tranexamic acid pharmacokinetics following intravenous, intramuscular, sub-cutaneous and oral administration in healthy volunteers
por: Kane, Zoe, et al.
Publicado: (2021)

Cost-effectiveness analysis of tranexamic acid for the treatment of traumatic brain injury, based on the results of the CRASH-3 randomised trial: a decision modelling approach
por: Williams, Jack, et al.
Publicado: (2020)

Clinical Validation of a Volumetric Absorptive Micro-Sampling Device for Pharmacokinetic Studies With Tranexamic Acid
por: Grassin-Delyle, Stanislas, et al.
Publicado: (2021)

Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial
por: Brenner, Amy, et al.
Publicado: (2019)

No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial
por: Dallaku, Kastriot, et al.
Publicado: (2019)

Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease
por: Ker, Katharine, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_7utci05r6cfjgrhm4ghcaehupe