Urinary Markers of Glomerular Injury in Diabetic Nephropathy

Diabetic nephropathy, the leading cause of renal failure worldwide, affects approximately one-third of all people with diabetes. Microalbuminuria is considered the first sign and the best predictor of progression to renal failure and cardiovascular events. However, albuminuria has several limitation...

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Detalles Bibliográficos
Autores principales: Cohen-Bucay, Abraham, Viswanathan, Gautham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356892/
https://www.ncbi.nlm.nih.gov/pubmed/22645683
http://dx.doi.org/10.1155/2012/146987
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author Cohen-Bucay, Abraham
Viswanathan, Gautham
author_facet Cohen-Bucay, Abraham
Viswanathan, Gautham
author_sort Cohen-Bucay, Abraham
collection PubMed
description Diabetic nephropathy, the leading cause of renal failure worldwide, affects approximately one-third of all people with diabetes. Microalbuminuria is considered the first sign and the best predictor of progression to renal failure and cardiovascular events. However, albuminuria has several limitations. Therefore, earlier, more sensitive and specific biomarkers with greater predictability are needed. The aim of this paper is to discuss the current literature on biomarkers of glomerular injury that have been implicated in diabetic kidney disease.
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spelling pubmed-33568922012-05-29 Urinary Markers of Glomerular Injury in Diabetic Nephropathy Cohen-Bucay, Abraham Viswanathan, Gautham Int J Nephrol Review Article Diabetic nephropathy, the leading cause of renal failure worldwide, affects approximately one-third of all people with diabetes. Microalbuminuria is considered the first sign and the best predictor of progression to renal failure and cardiovascular events. However, albuminuria has several limitations. Therefore, earlier, more sensitive and specific biomarkers with greater predictability are needed. The aim of this paper is to discuss the current literature on biomarkers of glomerular injury that have been implicated in diabetic kidney disease. Hindawi Publishing Corporation 2012-05-08 /pmc/articles/PMC3356892/ /pubmed/22645683 http://dx.doi.org/10.1155/2012/146987 Text en Copyright © 2012 A. Cohen-Bucay and G. Viswanathan. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Cohen-Bucay, Abraham
Viswanathan, Gautham
Urinary Markers of Glomerular Injury in Diabetic Nephropathy
title Urinary Markers of Glomerular Injury in Diabetic Nephropathy
title_full Urinary Markers of Glomerular Injury in Diabetic Nephropathy
title_fullStr Urinary Markers of Glomerular Injury in Diabetic Nephropathy
title_full_unstemmed Urinary Markers of Glomerular Injury in Diabetic Nephropathy
title_short Urinary Markers of Glomerular Injury in Diabetic Nephropathy
title_sort urinary markers of glomerular injury in diabetic nephropathy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356892/
https://www.ncbi.nlm.nih.gov/pubmed/22645683
http://dx.doi.org/10.1155/2012/146987
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