Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status

Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fib...

Descripción completa

Detalles Bibliográficos
Autores principales: Jaeger, T., Ring, J., Andres, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356914/
https://www.ncbi.nlm.nih.gov/pubmed/22649735
http://dx.doi.org/10.1155/2012/983421
_version_ 1782233607649099776
author Jaeger, T.
Ring, J.
Andres, C.
author_facet Jaeger, T.
Ring, J.
Andres, C.
author_sort Jaeger, T.
collection PubMed
description Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fibroxanthoma. In this review article clinical, histopathological and immunhistochemical features of Merkel cell carcinoma are reported. In addition, the role of Merkel cell polyomavirus is discussed.
format Online
Article
Text
id pubmed-3356914
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-33569142012-05-30 Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status Jaeger, T. Ring, J. Andres, C. J Skin Cancer Review Article Merkel cell carcinoma is a rare, but highly malignant tumor of the skin with high rates of metastasis and poor survival. Its incidence rate rises and is currently about 0.6/100000/year. Clinical differential diagnoses include basal cell carcinoma, cyst, amelanotic melanoma, lymphoma and atypical fibroxanthoma. In this review article clinical, histopathological and immunhistochemical features of Merkel cell carcinoma are reported. In addition, the role of Merkel cell polyomavirus is discussed. Hindawi Publishing Corporation 2012 2012-05-07 /pmc/articles/PMC3356914/ /pubmed/22649735 http://dx.doi.org/10.1155/2012/983421 Text en Copyright © 2012 T. Jaeger et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Jaeger, T.
Ring, J.
Andres, C.
Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_full Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_fullStr Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_full_unstemmed Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_short Histological, Immunohistological, and Clinical Features of Merkel Cell Carcinoma in Correlation to Merkel Cell Polyomavirus Status
title_sort histological, immunohistological, and clinical features of merkel cell carcinoma in correlation to merkel cell polyomavirus status
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3356914/
https://www.ncbi.nlm.nih.gov/pubmed/22649735
http://dx.doi.org/10.1155/2012/983421
work_keys_str_mv AT jaegert histologicalimmunohistologicalandclinicalfeaturesofmerkelcellcarcinomaincorrelationtomerkelcellpolyomavirusstatus
AT ringj histologicalimmunohistologicalandclinicalfeaturesofmerkelcellcarcinomaincorrelationtomerkelcellpolyomavirusstatus
AT andresc histologicalimmunohistologicalandclinicalfeaturesofmerkelcellcarcinomaincorrelationtomerkelcellpolyomavirusstatus

Ejemplares similares