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A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome

Irritable bowel syndrome (IBS), a disorder of the brain-gut axis, is characterised by the absence of reliable biological markers. Tryptophan is an essential amino acid that serves as a precursor to serotonin but which can alternatively be metabolised along the kynurenine pathway leading to the produ...

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Detalles Bibliográficos
Autores principales: Clarke, Gerard, McKernan, Declan P., Gaszner, Gabor, Quigley, Eamonn M., Cryan, John F., Dinan, Timothy G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357104/
https://www.ncbi.nlm.nih.gov/pubmed/22661947
http://dx.doi.org/10.3389/fphar.2012.00090

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