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A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome
Irritable bowel syndrome (IBS), a disorder of the brain-gut axis, is characterised by the absence of reliable biological markers. Tryptophan is an essential amino acid that serves as a precursor to serotonin but which can alternatively be metabolised along the kynurenine pathway leading to the produ...
Autores principales: | Clarke, Gerard, McKernan, Declan P., Gaszner, Gabor, Quigley, Eamonn M., Cryan, John F., Dinan, Timothy G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Research Foundation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357104/ https://www.ncbi.nlm.nih.gov/pubmed/22661947 http://dx.doi.org/10.3389/fphar.2012.00090 |
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