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Cellular Responses to the Metal-Binding Properties of Metformin

In recent decades, the antihyperglycemic biguanide metformin has been used extensively in the treatment of type 2 diabetes, despite continuing uncertainty over its direct target. In this article, using two independent approaches, we demonstrate that cellular actions of metformin are disrupted by int...

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Detalles Bibliográficos
Autores principales:	Logie, Lisa, Harthill, Jean, Patel, Kashyap, Bacon, Sandra, Hamilton, D. Lee, Macrae, Katherine, McDougall, Gordon, Wang, Huan-Huan, Xue, Lin, Jiang, Hua, Sakamoto, Kei, Prescott, Alan R., Rena, Graham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357267/ https://www.ncbi.nlm.nih.gov/pubmed/22492524 http://dx.doi.org/10.2337/db11-0961

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