Prevention of Autoimmune Diabetes by Ectopic Pancreatic β-Cell Expression of Interleukin-35

Interleukin (IL)-35 is a newly identified inhibitory cytokine used by T regulatory cells to control T cell–driven immune responses. However, the therapeutic potential of native, biologically active IL-35 has not been fully examined. Expression of the heterodimeric IL-35 cytokine was targeted to β-ce...

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Detalles Bibliográficos
Autores principales: Bettini, Maria, Castellaw, Ashley H., Lennon, Greig P., Burton, Amanda R., Vignali, Dario A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Immunology and Transplantation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357277/
https://www.ncbi.nlm.nih.gov/pubmed/22427377
http://dx.doi.org/10.2337/db11-0784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357277/
https://www.ncbi.nlm.nih.gov/pubmed/22427377
http://dx.doi.org/10.2337/db11-0784

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