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Prevention of Autoimmune Diabetes by Ectopic Pancreatic β-Cell Expression of Interleukin-35
Interleukin (IL)-35 is a newly identified inhibitory cytokine used by T regulatory cells to control T cell–driven immune responses. However, the therapeutic potential of native, biologically active IL-35 has not been fully examined. Expression of the heterodimeric IL-35 cytokine was targeted to β-ce...
Autores principales: | Bettini, Maria, Castellaw, Ashley H., Lennon, Greig P., Burton, Amanda R., Vignali, Dario A.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357277/ https://www.ncbi.nlm.nih.gov/pubmed/22427377 http://dx.doi.org/10.2337/db11-0784 |
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