α1-Acid Glycoprotein Decreases Neutrophil Migration and Increases Susceptibility to Sepsis in Diabetic Mice

The mechanisms underlying immune deficiency in diabetes are largely unknown. In the present study, we demonstrate that diabetic mice are highly susceptible to polymicrobial sepsis due to reduction in rolling, adhesion, and migration of leukocytes to the focus of infection. In addition, after sepsis...

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Detalles Bibliográficos
Autores principales: Spiller, Fernando, Carlos, Daniela, Souto, Fabrício O., de Freitas, Andressa, Soares, Fernanda S., Vieira, Silvio M., Paula, Francisco J.A., Alves-Filho, José C., Cunha, Fernando Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357278/
https://www.ncbi.nlm.nih.gov/pubmed/22415874
http://dx.doi.org/10.2337/db11-0825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357278/
https://www.ncbi.nlm.nih.gov/pubmed/22415874
http://dx.doi.org/10.2337/db11-0825

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