Recycling Between Cortisol and Cortisone in Human Splanchnic, Subcutaneous Adipose, and Skeletal Muscle Tissues In Vivo

11β-Hydroxysteroid dehydrogenase type 1 (11βHSD1) is a therapeutic target in metabolic syndrome because it catalyses reductase regeneration of cortisol from cortisone in adipose and liver. 11βHSD1 can also catalyze the reverse dehydrogenase reaction in vitro (e.g., if cofactor is limited). We used s...

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Detalles Bibliográficos
Autores principales: Hughes, Katherine A., Manolopoulos, Konstantinos N., Iqbal, Javaid, Cruden, Nicholas L., Stimson, Roland H., Reynolds, Rebecca M., Newby, David E., Andrew, Ruth, Karpe, Fredrik, Walker, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2012
Materias:
Methodology Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357308/
https://www.ncbi.nlm.nih.gov/pubmed/22511204
http://dx.doi.org/10.2337/db11-1345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357308/
https://www.ncbi.nlm.nih.gov/pubmed/22511204
http://dx.doi.org/10.2337/db11-1345

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