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Evaluation of Allele-Specific Somatic Changes of Genome-Wide Association Study Susceptibility Alleles in Human Colorectal Cancers

BACKGROUND: Tumors frequently exhibit loss of tumor suppressor genes or allelic gains of activated oncogenes. A significant proportion of cancer susceptibility loci in the mouse show somatic losses or gains consistent with the presence of a tumor susceptibility or resistance allele. Thus, allele-spe...

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Detalles Bibliográficos
Autores principales:	Gerber, Madelyn M., Hampel, Heather, Schulz, Nathan P., Fernandez, Soledad, Wei, Lai, Zhou, Xiao-Ping, de la Chapelle, Albert, Toland, Amanda Ewart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357346/ https://www.ncbi.nlm.nih.gov/pubmed/22629442 http://dx.doi.org/10.1371/journal.pone.0037672

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