Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development

For therapeutic purposes, non-small cell lung cancer (NSCLC) has traditionally been regarded as a single disease. However, recent evidence suggest that the two major subtypes of NSCLC, adenocarcinoma (AC) and squamous cell carcinoma (SqCC) respond differently to both molecular targeted and new gener...

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Detalles Bibliográficos
Autores principales: Lockwood, William W., Wilson, Ian M., Coe, Bradley P., Chari, Raj, Pikor, Larissa A., Thu, Kelsie L., Solis, Luisa M., Nunez, Maria I., Behrens, Carmen, Yee, John, English, John, Murray, Nevin, Tsao, Ming-Sound, Minna, John D., Gazdar, Adi F., Wistuba, Ignacio I., MacAulay, Calum E., Lam, Stephen, Lam, Wan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357406/
https://www.ncbi.nlm.nih.gov/pubmed/22629454
http://dx.doi.org/10.1371/journal.pone.0037775

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