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Effects of Acute Tryptophan Depletion on Brain Serotonin Function and Concentrations of Dopamine and Norepinephrine in C57BL/6J and BALB/cJ Mice
Acute tryptophan depletion (ATD) is a method of lowering brain serotonin (5-HT). Administration of large neutral amino acids (LNAA) limits the transport of endogenous tryptophan (TRP) across the blood brain barrier by competition with other LNAAs and subsequently decreases serotonergic neurotransmis...
Autores principales: | Biskup, Caroline Sarah, Sánchez, Cristina L., Arrant, Andrew, Van Swearingen, Amanda E. D., Kuhn, Cynthia, Zepf, Florian Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357407/ https://www.ncbi.nlm.nih.gov/pubmed/22629305 http://dx.doi.org/10.1371/journal.pone.0035916 |
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