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Identification of MicroRNAs Inhibiting TGF-β-Induced IL-11 Production in Bone Metastatic Breast Cancer Cells
Development of bone metastases is dependent on the cancer cell-bone cell interactions in the bone microenvironment. Transforming growth factor β (TGF-β) is released from bone during osteoclastic bone resorption and induces production of osteolytic factors, such as interleukin 11 (IL-11), in breast c...
Autores principales: | Pollari, Sirkku, Leivonen, Suvi-Katri, Perälä, Merja, Fey, Vidal, Käkönen, Sanna-Maria, Kallioniemi, Olli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357420/ https://www.ncbi.nlm.nih.gov/pubmed/22629385 http://dx.doi.org/10.1371/journal.pone.0037361 |
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