Homozygosity Mapping on a Single Patient—Identification of Homozygous Regions of Recent Common Ancestry by Using Population Data

Homozygosity mapping has played an important role in detecting recessive mutations using families of consanguineous marriages. However, detection of regions identical and homozygosity by descent (HBD) when family data are not available, or when relationships are unknown, is still a challenge. Making...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Yang, Wanling, Ying, Dingge, Cherny, Stacey S, Hildebrandt, Friedhelm, Sham, Pak Chung, Lau, Yu Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2011
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357498/
https://www.ncbi.nlm.nih.gov/pubmed/21309031
http://dx.doi.org/10.1002/humu.21432

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