Staurosporine Inhibits Frequency-Dependent Myofilament Desensitization in Intact Rabbit Cardiac Trabeculae

Myofilament calcium sensitivity decreases with frequency in intact healthy rabbit trabeculae and associates with Troponin I and Myosin light chain-2 phosphorylation. We here tested whether serine-threonine kinase activity is primarily responsible for this frequency-dependent modulations of myofilame...

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Detalles Bibliográficos
Autores principales: Varian, Kenneth D., Biesiadecki, Brandon J., Ziolo, Mark T., Davis, Jonathan P., Janssen, Paul M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357507/
https://www.ncbi.nlm.nih.gov/pubmed/22649731
http://dx.doi.org/10.1155/2012/290971

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357507/
https://www.ncbi.nlm.nih.gov/pubmed/22649731
http://dx.doi.org/10.1155/2012/290971

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