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In Vivo Consequences of Disrupting SH3-Mediated Interactions of the Inducible T-Cell Kinase

ITK-SH3-mediated interactions, both with exogenous ligands and via intermolecular self-association with ITK-SH2, have been shown to be important for regulation of ITK activity. The biological significance of these competing SH3 interactions is not completely understood. A mutant of ITK where substit...

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Detalles Bibliográficos
Autores principales:	Levytskyy, Roman M., Hirve, Nupura, Guimond, David M., Min, Lie, Andreotti, Amy H., Tsoukas, Constantine D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357558/ https://www.ncbi.nlm.nih.gov/pubmed/22649724 http://dx.doi.org/10.1155/2012/694386

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