Physiologically Based Toxicokinetic Modelling as a Tool to Support Risk Assessment: Three Case Studies

In this contribution we present three case studies of physiologically based toxicokinetic (PBTK) modelling in regulatory risk assessment. (1) Age-dependent lower enzyme expression in the newborn leads to bisphenol A (BPA) blood levels which are near the levels of the tolerated daily intake (TDI) at...

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Detalles Bibliográficos
Autores principales: Mielke, Hans, Gundert-Remy, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357559/
https://www.ncbi.nlm.nih.gov/pubmed/22649449
http://dx.doi.org/10.1155/2012/359471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357559/
https://www.ncbi.nlm.nih.gov/pubmed/22649449
http://dx.doi.org/10.1155/2012/359471

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