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Physiologically Based Toxicokinetic Modelling as a Tool to Support Risk Assessment: Three Case Studies
In this contribution we present three case studies of physiologically based toxicokinetic (PBTK) modelling in regulatory risk assessment. (1) Age-dependent lower enzyme expression in the newborn leads to bisphenol A (BPA) blood levels which are near the levels of the tolerated daily intake (TDI) at...
Autores principales: | Mielke, Hans, Gundert-Remy, Ursula |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357559/ https://www.ncbi.nlm.nih.gov/pubmed/22649449 http://dx.doi.org/10.1155/2012/359471 |
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