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New Protein Vector ApE1 for Targeted Delivery of Anticancer Drugs

A new chimeric gene ApE1 encoding the receptor-binding domain of the human alpha-fetoprotein fused to a sequence of 22 glutamic acid residues was constructed. A new bacterial producer strain E. coli SHExT7 ApE1 was selected for ApE1 production in a soluble state. A simplified method was developed to...

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Detalles Bibliográficos
Autores principales: Pozdniakova, N. V., Gorokhovets, N. V., Gukasova, N. V., Bereznikova, A. V., Severin, E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357585/
https://www.ncbi.nlm.nih.gov/pubmed/22649278
http://dx.doi.org/10.1155/2012/469756

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