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Modulation of iron metabolism in aging and in Alzheimer's disease: relevance of the choroid plexus
Iron is essential for mammalian cellular homeostasis. However, in excess, it promotes free radical formation and is associated with aging-related progressive deterioration and with neurodegenerative disorders such as Alzheimer's disease (AD). There are no mechanisms to excrete iron, which makes...
Autores principales: | Mesquita, Sandro D., Ferreira, Ana C., Sousa, João C., Santos, Nadine C., Correia-Neves, Margarida, Sousa, Nuno, Palha, Joana A., Marques, Fernanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357636/ https://www.ncbi.nlm.nih.gov/pubmed/22661928 http://dx.doi.org/10.3389/fncel.2012.00025 |
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