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Mapping Neural Circuits with Activity-Dependent Nuclear Import of a Transcription Factor
Nuclear factor of activated T cells (NFAT) is a calcium-responsive transcription factor. We describe here an NFAT-based neural tracing method—CaLexA (calcium-dependent nuclear import of Lex A)—for labeling active neurons in behaving animals. In this system, sustained neural activity induces nuclear...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Informa Healthcare
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357894/ https://www.ncbi.nlm.nih.gov/pubmed/22236090 http://dx.doi.org/10.3109/01677063.2011.642910 |