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Mapping Neural Circuits with Activity-Dependent Nuclear Import of a Transcription Factor

Nuclear factor of activated T cells (NFAT) is a calcium-responsive transcription factor. We describe here an NFAT-based neural tracing method—CaLexA (calcium-dependent nuclear import of Lex A)—for labeling active neurons in behaving animals. In this system, sustained neural activity induces nuclear...

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Detalles Bibliográficos
Autores principales: Masuyama, Kaoru, Zhang, Yi, Rao, Yi, Wang, Jing W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Informa Healthcare 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357894/
https://www.ncbi.nlm.nih.gov/pubmed/22236090
http://dx.doi.org/10.3109/01677063.2011.642910