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Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders
Dysfunctional emotion regulation is often reported in affective disorders, but it is unclear whether this dysfunction concerns initial processing of emotional input or regulation of resulting emotion. The present study addressed these aspects in 27 depressive and 15 borderline personality disorder p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357925/ https://www.ncbi.nlm.nih.gov/pubmed/22649719 http://dx.doi.org/10.1155/2012/156529 |
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author | Pietrek, Christian Popov, Tzvetan Steffen, Astrid Miller, Gregory A. Rockstroh, Brigitte |
author_facet | Pietrek, Christian Popov, Tzvetan Steffen, Astrid Miller, Gregory A. Rockstroh, Brigitte |
author_sort | Pietrek, Christian |
collection | PubMed |
description | Dysfunctional emotion regulation is often reported in affective disorders, but it is unclear whether this dysfunction concerns initial processing of emotional input or regulation of resulting emotion. The present study addressed these aspects in 27 depressive and 15 borderline personality disorder patients and 28 healthy controls who were instructed to either passively view unpleasant and neutral pictures or downregulate emotional responses by reappraisal, while neuromagnetic brain activity was measured. All three groups showed more early response to unpleasant than to neutral pictures, whereas patients failed to show subsequent activity suppression under instructions to down-regulate. This deficient emotion regulation was evident primarily in those subjects reporting high childhood adversity. Results support intact emotional input processing but impaired emotion regulation in affective disorders and indicate a moderating influence of early life stress. |
format | Online Article Text |
id | pubmed-3357925 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33579252012-05-30 Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders Pietrek, Christian Popov, Tzvetan Steffen, Astrid Miller, Gregory A. Rockstroh, Brigitte Depress Res Treat Clinical Study Dysfunctional emotion regulation is often reported in affective disorders, but it is unclear whether this dysfunction concerns initial processing of emotional input or regulation of resulting emotion. The present study addressed these aspects in 27 depressive and 15 borderline personality disorder patients and 28 healthy controls who were instructed to either passively view unpleasant and neutral pictures or downregulate emotional responses by reappraisal, while neuromagnetic brain activity was measured. All three groups showed more early response to unpleasant than to neutral pictures, whereas patients failed to show subsequent activity suppression under instructions to down-regulate. This deficient emotion regulation was evident primarily in those subjects reporting high childhood adversity. Results support intact emotional input processing but impaired emotion regulation in affective disorders and indicate a moderating influence of early life stress. Hindawi Publishing Corporation 2012 2012-05-10 /pmc/articles/PMC3357925/ /pubmed/22649719 http://dx.doi.org/10.1155/2012/156529 Text en Copyright © 2012 Christian Pietrek et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Pietrek, Christian Popov, Tzvetan Steffen, Astrid Miller, Gregory A. Rockstroh, Brigitte Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders |
title | Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders |
title_full | Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders |
title_fullStr | Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders |
title_full_unstemmed | Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders |
title_short | Neuromagnetic Indication of Dysfunctional Emotion Regulation in Affective Disorders |
title_sort | neuromagnetic indication of dysfunctional emotion regulation in affective disorders |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3357925/ https://www.ncbi.nlm.nih.gov/pubmed/22649719 http://dx.doi.org/10.1155/2012/156529 |
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