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Extent of Structural Asymmetry in Homodimeric Proteins: Prevalence and Relevance
Most homodimeric proteins have symmetric structure. Although symmetry is known to confer structural and functional advantage, asymmetric organization is also observed. Using a non-redundant dataset of 223 high-resolution crystal structures of biologically relevant homodimers, we address questions on...
Autores principales: | Swapna, Lakshmipuram Seshadri, Srikeerthana, Kuchi, Srinivasan, Narayanaswamy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358323/ https://www.ncbi.nlm.nih.gov/pubmed/22629324 http://dx.doi.org/10.1371/journal.pone.0036688 |
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