Bone Marrow Stromal Cells Modulate Mouse ENT1 Activity and Protect Leukemia Cells from Cytarabine Induced Apoptosis

BACKGROUND: Despite a high response rate to chemotherapy, the majority of patients with acute myeloid leukemia (AML) are destined to relapse due to residual disease in the bone marrow (BM). The tumor microenvironment is increasingly being recognized as a critical factor in mediating cancer cell surv...

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Detalles Bibliográficos
Autores principales: Macanas-Pirard, Patricia, Leisewitz, Andrea, Broekhuizen, Richard, Cautivo, Kelly, Barriga, Francisco M., Leisewitz, Francisco, Gidi, Victoria, Riquelme, Erick, Montecinos, Viviana P., Swett, Pilar, Besa, Pelayo, Ramirez, Pablo, Ocqueteau, Mauricio, Kalergis, Alexis M., Holt, Matthew, Rettig, Michael, DiPersio, John F., Nervi, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358339/
https://www.ncbi.nlm.nih.gov/pubmed/22629369
http://dx.doi.org/10.1371/journal.pone.0037203

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