Necrotizing infundibulo-hypophysitis: an entity too rare to be true?

We report a young woman with sudden and severe retroorbital headache, neck pain, and a large sellar mass extending to the suprasellar cistern. A presumptive diagnosis of non-secreting pituitary macroadenoma undergoing apoplexy was made and transphenoidal surgery performed. Histopathology revealed mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Gutenberg, Angelika, Caturegli, Patrizio, Metz, Imke, Martinez, Ramon, Mohr, Alexander, Brück, Wolfgang, Rohde, Veit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358537/
https://www.ncbi.nlm.nih.gov/pubmed/21479815
http://dx.doi.org/10.1007/s11102-011-0307-2
_version_ 1782233781365637120
author Gutenberg, Angelika
Caturegli, Patrizio
Metz, Imke
Martinez, Ramon
Mohr, Alexander
Brück, Wolfgang
Rohde, Veit
author_facet Gutenberg, Angelika
Caturegli, Patrizio
Metz, Imke
Martinez, Ramon
Mohr, Alexander
Brück, Wolfgang
Rohde, Veit
author_sort Gutenberg, Angelika
collection PubMed
description We report a young woman with sudden and severe retroorbital headache, neck pain, and a large sellar mass extending to the suprasellar cistern. A presumptive diagnosis of non-secreting pituitary macroadenoma undergoing apoplexy was made and transphenoidal surgery performed. Histopathology revealed mononuclear infiltration and marked non-hemorrhagic necrosis of the anterior pituitary consistent with a diagnosis of necrotizing infundibulo-hypophysitis. The possible pathogenesis of this rare variant of hypophysitis is discussed.
format Online
Article
Text
id pubmed-3358537
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-33585372012-05-31 Necrotizing infundibulo-hypophysitis: an entity too rare to be true? Gutenberg, Angelika Caturegli, Patrizio Metz, Imke Martinez, Ramon Mohr, Alexander Brück, Wolfgang Rohde, Veit Pituitary Article We report a young woman with sudden and severe retroorbital headache, neck pain, and a large sellar mass extending to the suprasellar cistern. A presumptive diagnosis of non-secreting pituitary macroadenoma undergoing apoplexy was made and transphenoidal surgery performed. Histopathology revealed mononuclear infiltration and marked non-hemorrhagic necrosis of the anterior pituitary consistent with a diagnosis of necrotizing infundibulo-hypophysitis. The possible pathogenesis of this rare variant of hypophysitis is discussed. Springer US 2011-04-10 2012 /pmc/articles/PMC3358537/ /pubmed/21479815 http://dx.doi.org/10.1007/s11102-011-0307-2 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Article
Gutenberg, Angelika
Caturegli, Patrizio
Metz, Imke
Martinez, Ramon
Mohr, Alexander
Brück, Wolfgang
Rohde, Veit
Necrotizing infundibulo-hypophysitis: an entity too rare to be true?
title Necrotizing infundibulo-hypophysitis: an entity too rare to be true?
title_full Necrotizing infundibulo-hypophysitis: an entity too rare to be true?
title_fullStr Necrotizing infundibulo-hypophysitis: an entity too rare to be true?
title_full_unstemmed Necrotizing infundibulo-hypophysitis: an entity too rare to be true?
title_short Necrotizing infundibulo-hypophysitis: an entity too rare to be true?
title_sort necrotizing infundibulo-hypophysitis: an entity too rare to be true?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358537/
https://www.ncbi.nlm.nih.gov/pubmed/21479815
http://dx.doi.org/10.1007/s11102-011-0307-2
work_keys_str_mv AT gutenbergangelika necrotizinginfundibulohypophysitisanentitytooraretobetrue
AT catureglipatrizio necrotizinginfundibulohypophysitisanentitytooraretobetrue
AT metzimke necrotizinginfundibulohypophysitisanentitytooraretobetrue
AT martinezramon necrotizinginfundibulohypophysitisanentitytooraretobetrue
AT mohralexander necrotizinginfundibulohypophysitisanentitytooraretobetrue
AT bruckwolfgang necrotizinginfundibulohypophysitisanentitytooraretobetrue
AT rohdeveit necrotizinginfundibulohypophysitisanentitytooraretobetrue

Ejemplares similares