Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway

Autosomal dominant polycystic kidney disease (ADPKD) is a progressive chronic kidney disease. To date there are no effective medicines to halt development and growth of cysts. In the present study, we explored novel effects of celecoxib (CXB), a COX-2 specific inhibitor, on primary cultures of human...

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Detalles Bibliográficos
Autores principales: Xu, Tao, Wang, Nian-Song, Fu, Li-Li, Ye, Chao-Yang, Yu, Sheng-Qiang, Mei, Chang-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358558/
https://www.ncbi.nlm.nih.gov/pubmed/22415852
http://dx.doi.org/10.1007/s11033-012-1611-2

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