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Infliximab Exerts No Direct Hepatotoxic Effect on HepG2 Cells In Vitro

BACKGROUND: Infliximab-induced hepatotoxicity is reported in several case studies involving patients with inflammatory bowel disease (IBD) and a direct hepatotoxic effect has been proposed. OBJECTIVE: The aim of this study was to determine the direct in vitro toxicity of infliximab. As a proof of pr...

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Detalles Bibliográficos
Autores principales: de Vries, Hilbert S., de Heij, Tineke, Roelofs, Henie M. J., te Morsche, Rene H. M., Peters, Wilbert H. M., de Jong, Dirk J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358583/
https://www.ncbi.nlm.nih.gov/pubmed/22535279
http://dx.doi.org/10.1007/s10620-012-2159-7