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Reconstructing cancer genomes from paired-end sequencing data
BACKGROUND: A cancer genome is derived from the germline genome through a series of somatic mutations. Somatic structural variants - including duplications, deletions, inversions, translocations, and other rearrangements - result in a cancer genome that is a scrambling of intervals, or "blocks&...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358655/ https://www.ncbi.nlm.nih.gov/pubmed/22537039 http://dx.doi.org/10.1186/1471-2105-13-S6-S10 |