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High-resolution genetic mapping with pooled sequencing
BACKGROUND: Modern genetics has been transformed by high-throughput sequencing. New experimental designs in model organisms involve analyzing many individuals, pooled and sequenced in groups for increased efficiency. However, the uncertainty from pooling and the challenge of noisy sequencing data de...
Autores principales: | Edwards, Matthew D, Gifford, David K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358661/ https://www.ncbi.nlm.nih.gov/pubmed/22537047 http://dx.doi.org/10.1186/1471-2105-13-S6-S8 |
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