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A context-based approach to identify the most likely mapping for RNA-seq experiments
BACKGROUND: Sequencing of mRNA (RNA-seq) by next generation sequencing technologies is widely used for analyzing the transcriptomic state of a cell. Here, one of the main challenges is the mapping of a sequenced read to its transcriptomic origin. As a simple alignment to the genome will fail to iden...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358662/ https://www.ncbi.nlm.nih.gov/pubmed/22537048 http://dx.doi.org/10.1186/1471-2105-13-S6-S9 |