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Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent

OBJECTIVE: To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES). METHOD: Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a con...

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Autores principales: Kim, Chul, Choi, Hee Eun, Kim, Byung Ok, Lim, Min Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Academy of Rehabilitation Medicine 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358683/
https://www.ncbi.nlm.nih.gov/pubmed/22639751
http://dx.doi.org/10.5535/arm.2012.36.2.254
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author Kim, Chul
Choi, Hee Eun
Kim, Byung Ok
Lim, Min Ho
author_facet Kim, Chul
Choi, Hee Eun
Kim, Byung Ok
Lim, Min Ho
author_sort Kim, Chul
collection PubMed
description OBJECTIVE: To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES). METHOD: Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a control group. The CR group received six to eight weeks of early cardiac rehabilitation program in a hospital setting, and sustained a self-exercise program for six months in a community. The control group was instructed to exercise by themselves after leaving the hospital. Nine months after the first onset of disease, we implemented a coronary angiography and compared the two groups. In addition, we divided the patients into three subgroups according to the generation of DES, and compared the rate of restenosis between the CR group and control group within these three subgroups. RESULTS: At 9 months, in-stent restenosis, measured as an in-segment late luminal loss (LLL) of the stented coronary area, was smaller in the CR group (n=52) 0.16±0.42 mm compared to the control group (n=51) 0.39±0.78 mm (p<0.05). A reduction of LLL in the CR group compared to the control group was consistent among the three different generations of DES. CONCLUSION: The CR program is strongly associated with a significant reduction in LLL in the stented coronary segments, regardless of the generation of DES.
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spelling pubmed-33586832012-05-25 Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent Kim, Chul Choi, Hee Eun Kim, Byung Ok Lim, Min Ho Ann Rehabil Med Original Article OBJECTIVE: To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES). METHOD: Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a control group. The CR group received six to eight weeks of early cardiac rehabilitation program in a hospital setting, and sustained a self-exercise program for six months in a community. The control group was instructed to exercise by themselves after leaving the hospital. Nine months after the first onset of disease, we implemented a coronary angiography and compared the two groups. In addition, we divided the patients into three subgroups according to the generation of DES, and compared the rate of restenosis between the CR group and control group within these three subgroups. RESULTS: At 9 months, in-stent restenosis, measured as an in-segment late luminal loss (LLL) of the stented coronary area, was smaller in the CR group (n=52) 0.16±0.42 mm compared to the control group (n=51) 0.39±0.78 mm (p<0.05). A reduction of LLL in the CR group compared to the control group was consistent among the three different generations of DES. CONCLUSION: The CR program is strongly associated with a significant reduction in LLL in the stented coronary segments, regardless of the generation of DES. Korean Academy of Rehabilitation Medicine 2012-04 2012-04-30 /pmc/articles/PMC3358683/ /pubmed/22639751 http://dx.doi.org/10.5535/arm.2012.36.2.254 Text en Copyright © 2012 by Korean Academy of Rehabilitation Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Kim, Chul
Choi, Hee Eun
Kim, Byung Ok
Lim, Min Ho
Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
title Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
title_full Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
title_fullStr Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
title_full_unstemmed Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
title_short Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
title_sort impact of exercise-based cardiac rehabilitation on in-stent restenosis with different generations of drug eluting stent
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358683/
https://www.ncbi.nlm.nih.gov/pubmed/22639751
http://dx.doi.org/10.5535/arm.2012.36.2.254
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