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Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent
OBJECTIVE: To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES). METHOD: Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a con...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Academy of Rehabilitation Medicine
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358683/ https://www.ncbi.nlm.nih.gov/pubmed/22639751 http://dx.doi.org/10.5535/arm.2012.36.2.254 |
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author | Kim, Chul Choi, Hee Eun Kim, Byung Ok Lim, Min Ho |
author_facet | Kim, Chul Choi, Hee Eun Kim, Byung Ok Lim, Min Ho |
author_sort | Kim, Chul |
collection | PubMed |
description | OBJECTIVE: To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES). METHOD: Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a control group. The CR group received six to eight weeks of early cardiac rehabilitation program in a hospital setting, and sustained a self-exercise program for six months in a community. The control group was instructed to exercise by themselves after leaving the hospital. Nine months after the first onset of disease, we implemented a coronary angiography and compared the two groups. In addition, we divided the patients into three subgroups according to the generation of DES, and compared the rate of restenosis between the CR group and control group within these three subgroups. RESULTS: At 9 months, in-stent restenosis, measured as an in-segment late luminal loss (LLL) of the stented coronary area, was smaller in the CR group (n=52) 0.16±0.42 mm compared to the control group (n=51) 0.39±0.78 mm (p<0.05). A reduction of LLL in the CR group compared to the control group was consistent among the three different generations of DES. CONCLUSION: The CR program is strongly associated with a significant reduction in LLL in the stented coronary segments, regardless of the generation of DES. |
format | Online Article Text |
id | pubmed-3358683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Korean Academy of Rehabilitation Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-33586832012-05-25 Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent Kim, Chul Choi, Hee Eun Kim, Byung Ok Lim, Min Ho Ann Rehabil Med Original Article OBJECTIVE: To compare the rate of restenosis between a cardiac rehabilitation (CR) group and a control group within three different generations of drug eluting stents (DES). METHOD: Patients who received DES due to an acute coronary syndrome were included. They were divided into a CR group and a control group. The CR group received six to eight weeks of early cardiac rehabilitation program in a hospital setting, and sustained a self-exercise program for six months in a community. The control group was instructed to exercise by themselves after leaving the hospital. Nine months after the first onset of disease, we implemented a coronary angiography and compared the two groups. In addition, we divided the patients into three subgroups according to the generation of DES, and compared the rate of restenosis between the CR group and control group within these three subgroups. RESULTS: At 9 months, in-stent restenosis, measured as an in-segment late luminal loss (LLL) of the stented coronary area, was smaller in the CR group (n=52) 0.16±0.42 mm compared to the control group (n=51) 0.39±0.78 mm (p<0.05). A reduction of LLL in the CR group compared to the control group was consistent among the three different generations of DES. CONCLUSION: The CR program is strongly associated with a significant reduction in LLL in the stented coronary segments, regardless of the generation of DES. Korean Academy of Rehabilitation Medicine 2012-04 2012-04-30 /pmc/articles/PMC3358683/ /pubmed/22639751 http://dx.doi.org/10.5535/arm.2012.36.2.254 Text en Copyright © 2012 by Korean Academy of Rehabilitation Medicine http://creativecommons.org/licenses/by-nc/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted noncommercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Chul Choi, Hee Eun Kim, Byung Ok Lim, Min Ho Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent |
title | Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent |
title_full | Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent |
title_fullStr | Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent |
title_full_unstemmed | Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent |
title_short | Impact of Exercise-based Cardiac Rehabilitation on In-stent Restenosis with Different Generations of Drug Eluting Stent |
title_sort | impact of exercise-based cardiac rehabilitation on in-stent restenosis with different generations of drug eluting stent |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3358683/ https://www.ncbi.nlm.nih.gov/pubmed/22639751 http://dx.doi.org/10.5535/arm.2012.36.2.254 |
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