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Depletion of OLFM4 gene inhibits cell growth and increases sensitization to hydrogen peroxide and tumor necrosis factor-alpha induced-apoptosis in gastric cancer cells

BACKGROUND: Human olfactomedin 4 (OLFM4) gene is a secreted glycoprotein more commonly known as the anti-apoptotic molecule GW112. OLFM4 is found to be frequently up-regulated in many types of human tumors including gastric cancer and it was believed to play significant role in the progression of ga...

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Detalles Bibliográficos
Autores principales: Liu, Rui-hua, Yang, Mei-hua, Xiang, Hua, Bao, Li-ming, Yang, Hua-an, Yue, Li-wen, Jiang, Xue, Ang, Na, Wu, Li-ya, Huang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359197/
https://www.ncbi.nlm.nih.gov/pubmed/22471589
http://dx.doi.org/10.1186/1423-0127-19-38