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Analysis of high-depth sequence data for studying viral diversity: a comparison of next generation sequencing platforms using Segminator II

BACKGROUND: Next generation sequencing provides detailed insight into the variation present within viral populations, introducing the possibility of treatment strategies that are both reactive and predictive. Current software tools, however, need to be scaled up to accommodate for high-depth viral d...

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Detalles Bibliográficos
Autores principales: Archer, John, Baillie, Greg, Watson, Simon J, Kellam, Paul, Rambaut, Andrew, Robertson, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359224/
https://www.ncbi.nlm.nih.gov/pubmed/22443413
http://dx.doi.org/10.1186/1471-2105-13-47