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Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia. The potassium current I(Ks )is essential for cardiac repolarization. Gain-of-function mutations in K(V)7.1, the pore-forming α-subunit of the I(Ks )channel, have been associated with AF. We hypothesized that early-onset lone AF is a...

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Detalles Bibliográficos
Autores principales:	Olesen, Morten S, Bentzen, Bo H, Nielsen, Jonas B, Steffensen, Annette B, David, Jens-Peter, Jabbari, Javad, Jensen, Henrik K, Haunsø, Stig, Svendsen, Jesper H, Schmitt, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359244/ https://www.ncbi.nlm.nih.gov/pubmed/22471742 http://dx.doi.org/10.1186/1471-2350-13-24

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