Cargando…
Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement
BACKGROUND: Arterial stiffness is a major contributor to cardiovascular diseases. Because current methods of measuring arterial stiffness are technically demanding, the purpose of this study was to develop a simple method of evaluating arterial stiffness using oscillometric blood pressure measuremen...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359259/ https://www.ncbi.nlm.nih.gov/pubmed/22325084 http://dx.doi.org/10.1186/1475-925X-11-6 |
_version_ | 1782233847571677184 |
---|---|
author | Komine, Hidehiko Asai, Yoshiyuki Yokoi, Takashi Yoshizawa, Mutsuko |
author_facet | Komine, Hidehiko Asai, Yoshiyuki Yokoi, Takashi Yoshizawa, Mutsuko |
author_sort | Komine, Hidehiko |
collection | PubMed |
description | BACKGROUND: Arterial stiffness is a major contributor to cardiovascular diseases. Because current methods of measuring arterial stiffness are technically demanding, the purpose of this study was to develop a simple method of evaluating arterial stiffness using oscillometric blood pressure measurement. METHODS: Blood pressure was conventionally measured in the left upper arm of 173 individuals using an inflatable cuff. Using the time series of occlusive cuff pressure and the amplitudes of pulse oscillations, we calculated local slopes of the curve between the decreasing cuff pressure and corresponding arterial volume. Whole pressure-volume curve was derived from numerical integration of the local slopes. The curve was fitted using an equation and we identified a numerical coefficient of the equation as an index of arterial stiffness (Arterial Pressure-volume Index, API). We also measured brachial-ankle (baPWV) PWV and carotid-femoral (cfPWV) PWV using a vascular testing device and compared the values with API. Furthermore, we assessed carotid arterial compliance using ultrasound images to compare with API. RESULTS: The slope of the calculated pressure-volume curve was steeper for compliant (low baPWV or cfPWV) than stiff (high baPWV or cfPWV) arteries. API was related to baPWV (r = -0.53, P < 0.05), cfPWV (r = -0.49, P < 0.05), and carotid arterial compliance (r = 0.32, P < 0.05). A stepwise multiple regression analysis demonstrated that baPWV and carotid arterial compliance were the independent determinants of API, and that API was the independent determinant of baPWV and carotid arterial compliance. CONCLUSIONS: These results suggest that our method can simply and simultaneously evaluate arterial stiffness and blood pressure based on oscillometric measurements of blood pressure. |
format | Online Article Text |
id | pubmed-3359259 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-33592592012-06-01 Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement Komine, Hidehiko Asai, Yoshiyuki Yokoi, Takashi Yoshizawa, Mutsuko Biomed Eng Online Research BACKGROUND: Arterial stiffness is a major contributor to cardiovascular diseases. Because current methods of measuring arterial stiffness are technically demanding, the purpose of this study was to develop a simple method of evaluating arterial stiffness using oscillometric blood pressure measurement. METHODS: Blood pressure was conventionally measured in the left upper arm of 173 individuals using an inflatable cuff. Using the time series of occlusive cuff pressure and the amplitudes of pulse oscillations, we calculated local slopes of the curve between the decreasing cuff pressure and corresponding arterial volume. Whole pressure-volume curve was derived from numerical integration of the local slopes. The curve was fitted using an equation and we identified a numerical coefficient of the equation as an index of arterial stiffness (Arterial Pressure-volume Index, API). We also measured brachial-ankle (baPWV) PWV and carotid-femoral (cfPWV) PWV using a vascular testing device and compared the values with API. Furthermore, we assessed carotid arterial compliance using ultrasound images to compare with API. RESULTS: The slope of the calculated pressure-volume curve was steeper for compliant (low baPWV or cfPWV) than stiff (high baPWV or cfPWV) arteries. API was related to baPWV (r = -0.53, P < 0.05), cfPWV (r = -0.49, P < 0.05), and carotid arterial compliance (r = 0.32, P < 0.05). A stepwise multiple regression analysis demonstrated that baPWV and carotid arterial compliance were the independent determinants of API, and that API was the independent determinant of baPWV and carotid arterial compliance. CONCLUSIONS: These results suggest that our method can simply and simultaneously evaluate arterial stiffness and blood pressure based on oscillometric measurements of blood pressure. BioMed Central 2012-02-10 /pmc/articles/PMC3359259/ /pubmed/22325084 http://dx.doi.org/10.1186/1475-925X-11-6 Text en Copyright ©2012 Komine et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Komine, Hidehiko Asai, Yoshiyuki Yokoi, Takashi Yoshizawa, Mutsuko Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
title | Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
title_full | Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
title_fullStr | Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
title_full_unstemmed | Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
title_short | Non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
title_sort | non-invasive assessment of arterial stiffness using oscillometric blood pressure measurement |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359259/ https://www.ncbi.nlm.nih.gov/pubmed/22325084 http://dx.doi.org/10.1186/1475-925X-11-6 |
work_keys_str_mv | AT kominehidehiko noninvasiveassessmentofarterialstiffnessusingoscillometricbloodpressuremeasurement AT asaiyoshiyuki noninvasiveassessmentofarterialstiffnessusingoscillometricbloodpressuremeasurement AT yokoitakashi noninvasiveassessmentofarterialstiffnessusingoscillometricbloodpressuremeasurement AT yoshizawamutsuko noninvasiveassessmentofarterialstiffnessusingoscillometricbloodpressuremeasurement |