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Interaction of Virstatin with Human Serum Albumin: Spectroscopic Analysis and Molecular Modeling

Virstatin is a small molecule that inhibits Vibrio cholerae virulence regulation, the causative agent for cholera. Here we report the interaction of virstatin with human serum albumin (HSA) using various biophysical methods. The drug binding was monitored using different isomeric forms of HSA (N for...

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Detalles Bibliográficos
Autores principales: Chatterjee, Tanaya, Pal, Aritrika, Dey, Sucharita, Chatterjee, Barun K., Chakrabarti, Pinak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359307/
https://www.ncbi.nlm.nih.gov/pubmed/22649528
http://dx.doi.org/10.1371/journal.pone.0037468