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Analysis of the Paired TCR α- and β-chains of Single Human T Cells

Analysis of the paired i.e. matching TCR α- and β-chain rearrangements of single human T cells is required for a precise investigation of clonal diversity, tissue distribution and specificity of protective and pathologic T-cell mediated immune responses. Here we describe a multiplex RT-PCR based tec...

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Detalles Bibliográficos
Autores principales:	Kim, Song-Min, Bhonsle, Latika, Besgen, Petra, Nickel, Jens, Backes, Anna, Held, Kathrin, Vollmer, Sigrid, Dornmair, Klaus, Prinz, Joerg C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359365/ https://www.ncbi.nlm.nih.gov/pubmed/22649519 http://dx.doi.org/10.1371/journal.pone.0037338

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