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Macromolecular Crowding Directs Extracellular Matrix Organization and Mesenchymal Stem Cell Behavior

Microenvironments of biological cells are dominated in vivo by macromolecular crowding and resultant excluded volume effects. This feature is absent in dilute in vitro cell culture. Here, we induced macromolecular crowding in vitro by using synthetic macromolecular globules of nm-scale radius at phy...

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Detalles Bibliográficos
Autores principales: Zeiger, Adam S., Loe, Felicia C., Li, Ran, Raghunath, Michael, Van Vliet, Krystyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359376/
https://www.ncbi.nlm.nih.gov/pubmed/22649562
http://dx.doi.org/10.1371/journal.pone.0037904