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Macromolecular Crowding Directs Extracellular Matrix Organization and Mesenchymal Stem Cell Behavior
Microenvironments of biological cells are dominated in vivo by macromolecular crowding and resultant excluded volume effects. This feature is absent in dilute in vitro cell culture. Here, we induced macromolecular crowding in vitro by using synthetic macromolecular globules of nm-scale radius at phy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359376/ https://www.ncbi.nlm.nih.gov/pubmed/22649562 http://dx.doi.org/10.1371/journal.pone.0037904 |