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Global Activation of CD8(+) Cytotoxic T Lymphocytes Correlates with an Impairment in Regulatory T Cells in Patients with Generalized Vitiligo

Melanocyte-specific CD8(+) cytotoxic T lymphocytes (CTLs) play a pivotal role in vitiligo-induced depigmentation. Yet, the mechanisms underlying the high frequency of generalized autoimmune disorders associated with generalized vitiligo (GV) are unknown. We hypothesized that an imbalance between act...

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Detalles Bibliográficos
Autores principales:	Lili, Yang, Yi, Wei, Ji, Yang, Yue, Sun, Weimin, Shi, Ming, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359382/ https://www.ncbi.nlm.nih.gov/pubmed/22649532 http://dx.doi.org/10.1371/journal.pone.0037513

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