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Role of Medium- and Short-Chain L-3-Hydroxyacyl-CoA Dehydrogenase in the Regulation of Body Weight and Thermogenesis
Dysregulation of fatty acid oxidation plays a pivotal role in the pathophysiology of obesity and insulin resistance. Medium- and short-chain-3-hydroxyacyl-coenzyme A (CoA) dehydrogenase (SCHAD) (gene name, hadh) catalyze the third reaction of the mitochondrial β-oxidation cascade, the oxidation of 3...
Autores principales: | Schulz, Nadja, Himmelbauer, Heinz, Rath, Michaela, van Weeghel, Michel, Houten, Sander, Kulik, Wim, Suhre, Karsten, Scherneck, Stephan, Vogel, Heike, Kluge, Reinhart, Wiedmer, Petra, Joost, Hans-Georg, Schürmann, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359510/ https://www.ncbi.nlm.nih.gov/pubmed/21990309 http://dx.doi.org/10.1210/en.2011-1547 |
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