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Role of Medium- and Short-Chain L-3-Hydroxyacyl-CoA Dehydrogenase in the Regulation of Body Weight and Thermogenesis

Dysregulation of fatty acid oxidation plays a pivotal role in the pathophysiology of obesity and insulin resistance. Medium- and short-chain-3-hydroxyacyl-coenzyme A (CoA) dehydrogenase (SCHAD) (gene name, hadh) catalyze the third reaction of the mitochondrial β-oxidation cascade, the oxidation of 3...

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Detalles Bibliográficos
Autores principales: Schulz, Nadja, Himmelbauer, Heinz, Rath, Michaela, van Weeghel, Michel, Houten, Sander, Kulik, Wim, Suhre, Karsten, Scherneck, Stephan, Vogel, Heike, Kluge, Reinhart, Wiedmer, Petra, Joost, Hans-Georg, Schürmann, Annette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359510/
https://www.ncbi.nlm.nih.gov/pubmed/21990309
http://dx.doi.org/10.1210/en.2011-1547

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