Cargando…

Prediction of susceptibility to major depression by a model of interactions of multiple functional genetic variants and environmental factors

Major depressive disorder (MDD) is the most common psychiatric disorder and the second overall cause of disability. Even though a significant amount of the variance in the MDD phenotype is explained by inheritance, specific genetic variants conferring susceptibility to MDD explain only a minimal pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wong, M-L, Dong, C, Andreev, V, Arcos-Burgos, M, Licinio, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359641/ https://www.ncbi.nlm.nih.gov/pubmed/22449891 http://dx.doi.org/10.1038/mp.2012.13

Ejemplares similares

Low-frequency and rare variants may contribute to elucidate the genetics of major depressive disorder
por: Yu, Chenglong, et al.
Publicado: (2018)

A latent genetic subtype of major depression identified by whole-exome genotyping data in a Mexican-American cohort
por: Yu, C, et al.
Publicado: (2017)

Association of PDE11A global haplotype with major depression and antidepressant drug response
por: Luo, Huai-Rong, et al.
Publicado: (2009)

A novel strategy for clustering major depression individuals using whole-genome sequencing variant data
por: Yu, Chenglong, et al.
Publicado: (2017)

The PHF21B gene is associated with major depression and modulates the stress response
por: Wong, M-L, et al.
Publicado: (2017)

cGMP Signaling, Phosphodiesterases and Major Depressive Disorder
por: Reierson, Gillian W, et al.
Publicado: (2011)

The nature of genetic and environmental susceptibility to multiple sclerosis
por: Goodin, Douglas S., et al.
Publicado: (2021)

Polygenic interactions with environmental adversity in the aetiology of major depressive disorder
por: Mullins, N., et al.
Publicado: (2016)

Genetic and Environmental Contribution to Major Depressive Disorder and Self-declared Depression
por: Fabbri, Chiara
Publicado: (2016)

Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans
por: Dong, C, et al.
Publicado: (2009)

A Genetic Susceptibility Mechanism for Major Depression: Combinations of polymorphisms Defined the Risk of Major Depression and Subpopulations
por: Wang, Yanfang, et al.
Publicado: (2015)

Role of the IL-1 Pathway in Dopaminergic Neurodegeneration and Decreased Voluntary Movement
por: Stojakovic, Andrea, et al.
Publicado: (2016)

Multiple sclerosis: Exploring the limits and implications of genetic and environmental susceptibility
por: Goodin, Douglas S., et al.
Publicado: (2023)

A two-locus genetic interaction between LPHN3 and 11q predicts ADHD severity and long-term outcome
por: Acosta, M T, et al.
Publicado: (2011)

BDNF genetic variants and methylation: effects on cognition in major depressive disorder
por: Ferrer, Alex, et al.
Publicado: (2019)

Neuroimmunomodulation in Major Depressive Disorder: Focus on Caspase 1, Inducible Nitric Oxide Synthase, and Interferon-Gamma
por: Inserra, Antonio, et al.
Publicado: (2018)

Lifestyle or Environmental Influences and Their Interaction With Genetic Susceptibility on the Risk of LADA
por: Carlsson, Sofia
Publicado: (2022)

Landscapes of bacterial and metabolic signatures and their interaction in major depressive disorders
por: Yang, Jian, et al.
Publicado: (2020)

5HTTLPR Genetic Variant and Major Depressive Disorder: A Review
por: Fratelli, Caroline, et al.
Publicado: (2020)

BDNF Genetic Variant and Its Genotypic Fluctuation in Major Depressive Disorder
por: Ferreira Fratelli, Caroline, et al.
Publicado: (2021)

Functional Genomics Analysis to Disentangle the Role of Genetic Variants in Major Depression
por: Pérez-Granado, Judith, et al.
Publicado: (2022)

Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model Analysis
por: McIntosh, Andrew M., et al.
Publicado: (2016)

Book Review: Cardiovascular Diseases: Genetic Susceptibility, Environmental Factors, and Their Interaction
por: Okolo, Chidinma Adanna, et al.
Publicado: (2018)

Elevated Stress-Hemoconcentration in Major Depression Is Normalized by Antidepressant Treatment: Secondary Analysis from a Randomized, Double-Blind Clinical Trial and Relevance to Cardiovascular Disease Risk
por: Wong, Ma-Li, et al.
Publicado: (2008)

The Influence of TEP1 and TERC Genetic Variants on the Susceptibility to Multiple Sclerosis
por: Rumšaitė, Gintarė, et al.
Publicado: (2023)

The Genetics of Major Depression
por: Flint, Jonathan, et al.
Publicado: (2014)

The Genetics of Major Depression
por: Flint, Jonathan, et al.
Publicado: (2014)

Immunopathogenic Interaction of Environmental Triggers and Genetic Susceptibility in Diabetes: Is Epigenetics the Missing Link?
por: Litherland, Sally A.
Publicado: (2008)

Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions
por: Barrett, Jennifer H, et al.
Publicado: (2015)

Migraine and major depression: localizing shared genetic susceptibility in different cell types of the nervous systems
por: Androulakis, X. Michelle, et al.
Publicado: (2023)

Association of multiple genetic variants with breast cancer susceptibility in the Han Chinese population
por: Li, Xu, et al.
Publicado: (2016)

Predicting the combined effect of multiple genetic variants
por: Liu, Mingming, et al.
Publicado: (2015)

Dvl3 polymorphism interacts with life events and pro-inflammatory cytokines to influence major depressive disorder susceptibility
por: Zhang, Jian, et al.
Publicado: (2018)

Interactions Between Genetic Variants and Environmental Factors Affect Risk of Esophageal Adenocarcinoma and Barrett’s Esophagus
por: Dong, Jing, et al.
Publicado: (2018)

HTRA1 Variants and the Interaction with Smoking Confer the Genetic Susceptibility to Ischemic Stroke
por: Tian, Yuanrui, et al.
Publicado: (2021)

MAOA uVNTR Genetic Variant and Major Depressive Disorder: A Systematic Review
por: Castro Gonçalves, Ana Beatriz, et al.
Publicado: (2022)

Common variants in FKBP5 gene and major depressive disorder (MDD) susceptibility: a comprehensive meta-analysis
por: Rao, Shuquan, et al.
Publicado: (2016)

A major genetic component of BSE susceptibility
por: Juling, Katrin, et al.
Publicado: (2006)

Genome-wide Interaction Study with Major Depression Identifies Novel Variants Associated with Cognitive Function
por: Thalamuthu, Anbupalam, et al.
Publicado: (2022)

Advances in schizophrenia research: glycobiology, white matter abnormalities, and their interactions
por: Licinio, Julio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dasnhkuvah3tf1bmj22qv8f106