Metformin Rescues the Myocardium from Doxorubicin-Induced Energy Starvation and Mitochondrial Damage in Rats

Clinical use of doxorubicin (DOX) is limited by its cardiotoxic side effects. Recent studies established that metformin (MET), an oral antidiabetic drug, possesses an antioxidant activity. However, whether it can protect against DOX-induced energy starvation and mitochondrial damage has not been rep...

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Detalles Bibliográficos
Autores principales: Ashour, Abdelkader E., Sayed-Ahmed, Mohamed M., Abd-Allah, Adel R., Korashy, Hesham M., Maayah, Zaid H., Alkhalidi, Hisham, Mubarak, Mohammed, Alhaider, Abdulqader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359722/
https://www.ncbi.nlm.nih.gov/pubmed/22666520
http://dx.doi.org/10.1155/2012/434195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359722/
https://www.ncbi.nlm.nih.gov/pubmed/22666520
http://dx.doi.org/10.1155/2012/434195

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