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TBC-8, a Putative RAB-2 GAP, Regulates Dense Core Vesicle Maturation in Caenorhabditis elegans

Dense core vesicles (DCVs) are thought to be generated at the late Golgi apparatus as immature DCVs, which subsequently undergo a maturation process through clathrin-mediated membrane remodeling events. This maturation process is required for efficient processing of neuropeptides within DCVs and for...

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Detalles Bibliográficos
Autores principales: Hannemann, Mandy, Sasidharan, Nikhil, Hegermann, Jan, Kutscher, Lena M., Koenig, Sabine, Eimer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359978/
https://www.ncbi.nlm.nih.gov/pubmed/22654674
http://dx.doi.org/10.1371/journal.pgen.1002722